ECE2023 Poster Presentations Late-Breaking (40 abstracts)
Systemic inflammation in paragangliomas and pheochromocytomas
Özge Özer , Merve Apaydin Kayer , Evrim Yilmaz , Medine Nur Kebapci , Aysen Akalin , Belgin Efe , Mustafa Fuat Acikalin & Goknur Yorulmaz
Eskisehir Osmangazi University, Meselik Campus, Turkey
Background: Paragangliomas (PGLs) and pheochromocytomas (PCCs) arise from chromaffin cells. We evaluated the inflammatory markers. The pan-immune-inflammation value (PIV) has recently been used as a new marker. Therefore, we evaluated the PIV association in patients with PGLs/PCCs.
Methods: In the study, the data of 82 patients with PGLs/PCCs who applied between 2005 and 2020 were collected retrospectively from the records. NLR (neutrophil/lymphocyte ratio), PIV (pan-immune-inflammation value), PLR (platelet/lymphocyte ratio) values were calculated with the parameters measured from peripheral blood. These patients were compared with 47 healthy controls.
Results: PIV measurement was found to be higher than that of the control group (P=0.028; P<0.05). NLR measurement was also statistically significantly different (P=0.001; P<0.01). According to the ROC analysis, the most appropriate cut-off value for PIV to identify groups is ≥296.87.
Conclusion: As far as is known, our study is the first study with PIV in this patient group. This value was found to be significantly higher in the patient group. More studies are needed before it can be used as a marker.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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