Endocrine Abstracts

Objective: The carbohydrate metabolism dysfunctions are common in critical ill patients with diabetes or stress hyperglycaemia and the correct management of them has an important prognostic value. Despite its limitations, capillary glucose (CG) was collected more than arterial glucose (gold standard) because of its good correlation. However, the usefulness of intermittent intersticial glucose monitoring (IGM) in keeping blood glucose within target range in critical ill patients its controversial. Therefore, we will evaluate IGM and CG correlation in critical ill patients with diabetes or stress hyperglycaemia.

Materials and Methods: Prospective longitudinal observational study with 6 diabetic or stress hyperglycaemia patients admitted to the Intensive Care Unit (ICU). Demographic (sex, age), clinical (DM, hypertension, obesity), hemodynamic (need for vasoactives) and metabolic (A1c-type glycosylated hemoglobin (HbA1c) determined by laboratory analysis, presence of angiopathic complications, CG and IGM measurements (in mg/dl)) variables were collected. The statistical analysis was performed with the IBM SPSS v.25 programme (Statistical significance P<0.05).

Results: 67% were males with a mean age of 65.5 ± 21.5 years. 100% were hypertensive and 50% obese. 67% were type 2 diabetic with a mean HbA1c 6.5 ± 1.6% and 75% had angiopathic complications. 67% required vasoactives. Statistical analysis shows a strong and positive correlation between CG and MIG values (r=0.8, P=0.0).

Conclusions: There is a strong and positive correlation between MIG and CG values, which highlights the probable usefulness of the first one in patients admitted to the ICU. Therefore, it could be feasible as a glycemic management tool in the critically ill patient by improving GC measurements limitations. More studies are needed for prove this.