ECE2023 Eposter Presentations Thyroid (128 abstracts)
Hashimoto’s thyroiditis associated with alopecia
Faten Haj Kacem Akid 1 , Raida Ben Salah 2 , Siddiqa Soomauroo 1 , Abdel Mouhaymen Missaoui 1 , Sarra Chouaib 1 , Faten Frikha 2 , Nabila Rekik Majdoub 1 , Zouheir Bahloul 2 & Mohamed Abid 1
1Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia, 2Hedi Chaker University Hospital, Department of Internal Medicine, Sfax, Tunisia
Introduction: Alopecia is an autoimmune disease (AID) affecting the hair follicles. Alopecia can become generalised and affect all hairy areas (universal alopecia). As with any AID, it may be associated with other AIDs. We report 2 cases of the association of alopecia with autoimmune thyroid disease (AITD).
Observation: The subjects were a man and a woman aged 48 and 54 years respectively. They presented with hypothyroidism. Hashimoto’s thyroiditis (HT) was diagnosed and they were treated with L-thyroxine susbtituion therapy with favourable outcome. The thyroid disease was preceded since 24 years by an alopecia universalis, which appeared at the age of 23 years in the case of the man. In the other patient, this hypothyroidism was preceded by 2 other AIDs: alopecia universalis and vitiligo.
Discussion/Conclusion: Alopecia is a common condition with a significant psychosocial impact. It is a non-scarring alopecia, occurring most commonly in patches. The diagnosis is made clinically and does not require any further investigation in the absence of any particular symptoms. Alopecia can be associated with other AIDs, in particular thyroiditis, vitiligo and scleroderma. One study estimated the frequency of AITD in patients with alopecia to be 12.7%. Hypothyroidism was present in 92% of cases. It was found that alopecia in AITDs was most often severe, total or universal. Significantly higher levels of anti-thyroperoxidase antibodies and anti-thyroglobulins antibodies were found in the severe forms of alopecia.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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