Endocrine Abstracts

Introduction: Polycystic ovary syndrome is a pathology increasingly observed in women of childbearing age, in whom changes in hormonal and metabolic balance have been recorded

Aim: The aim of our work is to find Correlations between metabolic and hormonal parameters in PCOS patients

Methods: This is a retrospective descriptive and analytic study of patients with PCOS followed in the endocrinology department of Hedi Chaker University Hospital of Sfax, Tunisia between 2010 and 2022

Results: 50 patients were included. Mean age was 24 ± 6, 5 years. PCOS has been diagnosed at the age of 22, 5 ± 6, 17 years on average. Diabetes was found in 22% of cases overall, dysthyroidism was found in 24% of cases. However, 4% of patients were dyslipidemic. Obesity was noted in 14% of patients and 4% presented a cardiovascular event.12 women of 32 (37%) have metabolic syndrome. Prolactin was inversely correlated with LDlevel (r=-0,444). No correlation was found between HBA1C and testosterone (r= -0,277, P=0, 54). HBA1C was correlated with estrogen levels(r=0, 85, P= 0, 05). Fasting blood sugar was not correlated with FSH levels (r= -3,57, P= 0,62). The same goes for the correlation between cholesterol and estrogen levels (r=-1,04, P= 0,57).

Conclusion: This study showed a very probable relationship between metabolic and hormonal parameters. Taking these relationships into account is essential in the care of our patients.