Endocrine Abstracts

Pituitary adenomas arise from adenohypophyseal cells and progress with increased comorbidity and mortality. It is important to examine the diagnosis, prevalence, course and treatment of the subgroups of the disease in our country because pituitary adenomas are seen in the most productive periods of life and have important clinical results. In our study, 667 pituitary adenoma patients who applied to Eskişehir Osmangazi University Medical Faculty Hospital Endocrinology Department between 1980-2018 were evaluated retrospectively and observationally. The information of the patients was scanned from the hospital information management system and outpatient clinic patient files. Scanned information; age, gender, age of diagnosis, follow-up year, application complaint, size, location, hormone levels at the time of diagnosis and after treatment, type of medical treatment used, number and type of operation of pituitary adenoma, before medical or surgical treatment and post-adenoma size and if any, residual/recurrent pituitary adenoma size, chiasma compression, postoperative hormone activity, history of RT for adenoma. 171 (25.6%) were nonfunctional adenomas, 356 (53.4%) were prolactinomas, 121 (18.1%) were acromegaly, 16 (2.4%) were Cushing disease and 3 (0.4%) were TSHoma. 340 (51.1%) microadenomas, 195 (29.1%) macroadenomas, 132 (19.8%) invasive macroadenomas were detected. It should be kept in mind that delay in diagnosis will cause important problems such as decrease in quality of life, disability, preparing the ground for additional diseases, and showing a mortal course. As a result, the information obtained from the careful examination and the request for the relevant laboratory and radiological tests will lead us to early diagnosis.