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Endocrine Abstracts (2023) 90 EP1129 | DOI: 10.1530/endoabs.90.EP1129

National Institute of Nutrition and Food Technology, Department A, Tunis, Tunisia


Introduction : Poor compliance in chronic diseases, including diabetes mellitus, is a major and frequent problem, with serious consequences on morbidity and mortality of diabetics.

Objective: The aim was to assess adherence to antidiabetic treatment and to determine the consequences of poor compliance.

Patients and methods : This was a descriptive cross-sectional study conducted in the National Institute of Nutrition. 200 type 2 diabetic patients hospitalized between May and September 2022 were included. For each patient, we conducted a thorough interview and a biological check-up.

Results: The average age of our population was 58.56 ± 8.9 years with a female predominance of 66%. The average age of diabetes was 13.16 ± 7.8 years with an average HbA1c of 10.28 ± 2% and fasting blood glucose of 12.13 ± 5.42 mmol/l. 1/5 of our population did not accept their diabetes. The majority of our patients were on Oral-Diabetic-Agents (ODA), 21% on insulin and 39% on ODA and insulin. Diabetes was complicated by retinopathy, nephropathy and neuropathy in 38.5%, 17% and 66.5% of cases respectively. 4/5 of our patients were adherent to the treatments. We noted a decrease in doses in 15% and omission of the usual doses in 22.5% of cases. There was a statistically significant relationship between adherence to treatment and acceptance of the diagnosis of diabetes (P=0.03), retinopathy (P=0.009) and HBA1C (P=0.001).

Conclusion: The lack of awareness of this problem leads to unnecessary intensification of antidiabetic treatment and may explain the large number of patients put on insulin.

Volume 90

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

European Society of Endocrinology 

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