Endocrine Abstracts

Keywords: sugar substitute agent exposures, nutritional biology, neuroendocrine system, oxytocinHuman homeostasis is maintained by the complex functioning of the psycho-neuroendocrine-immune system. If a disturbance is generated in this neuroendocrine system for any reason, it can trigger pathogenic processes. One of the factors disturbing homeostasis today may be changes in dietary habits, e.g. through the use of undue sweeteners (e.g. stevia, xylitol e...

Certain endocrine disrupting chemicals (EDCs) are known to disrupt the thyroid hormone system. Thyroid hormone (TH) levels are physiologically regulated by the hypothalamic–pituitary–thyroid (HPT) axis, a tight feedback loop, whereby low levels of T4 stimulate an upregulation of TSH, and conversely if T4 levels are raised. Low levels of T4 (with chronic upregulation of TSH) can lead to thyroid hyperplasia – an outcome that is recognised by regulatory groups for ...

Introduction: Endocrine complications are common in beta thalassemia major (BTM) patients receiving blood transfusions. Chelation therapy has a role in preventing such complications. However, patients may have difficulties adhering to chelation therapy. We aimed in this study to determine the endocrine complications in BTM patients.Methods: This was a descriptive study with cross-sectional data collection over a 6 month period from February 2022 to July ...

Background: Our bodies function optimally when we align our eating & sleeping patterns with our circadian rhythms, the innate 24-hour cycles that tell our bodies when to wake up, when to eat and when to fall asleep. Chronically disrupting this rhythm by eating late night meals & sleep could be a recipe for Hypertension, CVD, and metabolic trouble.Aim and objective: The aim of this study is to investigate whether there was a relationship between m...

Background: Our bodies function optimally when we align our eating & sleeping patterns with our circadian rhythms, the innate 24-hour cycles that tell our bodies when to wake up, when to eat and when to fall asleep. Chronically disrupting this rhythm by eating late night meals & sleep could be a recipe for Diabetes, CVD, and metabolic trouble.Aim and objective: The aim of this study is to investigate whether there was a relationship between morni...

In Wuhan China in December 2019, cases of severe atypical viral pneumonia emerged, and the World Health Organization declared COVID-19 a pandemic. In this critical context, health workers were on the front lines, directly participating in the evaluation, diagnosis, and treatment of patients with COVID-19. The objective of our work was to evaluate stress and burnout in health workers and to measure hair cortisol levels as a stress biomarker during the second wave.<p class="...

Introduction: Transgender people are a diverse population affected by a variety of negative health indicators. Studies report, among other conditions, a high prevalence of mental health problems and substance abuse. However, there are still health issues that have been poorly analyzed and long-term longitudinal follow-up studies are scarce.Objective: The aim of this study is to deep into the demographic characteristics and the psychosocial profile of tra...

Mitochondria play an important role in generating energy, and they are essential to cell survival. Mitochondria have varieties of functions, such as regulating intracellular calcium concentration and signal transduction, controlling hormone synthesis, inflammatory responses, and free radicals. In particular this research is interested in the mitochondria in kidney tubular cell. Since mitochondria in tubular cells play an important role in supplying energy, removal of waste and...

Keywords: short stature, Noonan syndrome, Prader-Willi syndrome, Silver-Russell syndrome, genetic syndromesIntroduction: Short stature is one of the major components of dysmorphic syndromes. Growth failure may be due to a wide variety of mechanisms, either related to the growth hormone (GH)/insulin-like growth factor axis or to underlying unknown pathologies. At present, GH therapy is used in most syndromic disorders, although long-term studies evaluatin...

Introduction: Polycystic ovary syndrome (PCOS) is a complex condition with multi-systemic implications that can greatly impact patients’ lives. To understand and deliver the varied needs of people with PCOS, a substantial onus lies on PCOS researchers to objectively study patient data and formulate evidence-based recommendations. Equitable research is crucial to ensure fair representation of people of various ethnicities and stratify population-specific analysis to have g...