ECE2023 Eposter Presentations Endocrine-related Cancer (80 abstracts)
Mesenteric paraganglioma with a late-onset metastases accelerated after delayed surgery
Ewelina Rzepka 1 , Mari Minasyan 1 , Elwira Przybylik-Mazurek 1 , Magdalena Ulatowska-Białas 2 , Marta Opalinska 1 , Anna Sowa-Staszczak 1 , Aleksandra Gilis-Januszewska 1 & Alicja Hubalewska-Dydejczyk 1
1Jagiellonian University Medical College, Chair and Department of Endocrinology, Cracow, Poland; 2Jagiellonian University Medical College, Department of Pathomorphology, Cracow, Poland.
Mesenteric paragangliomas are a rare entity; consequently, 20 cases have been reported to date. Although often found incidentally and considered benign, they have potential to metastasize. We present a case of 63-year old man with a 11-year history of the mesenteric paraganglioma. The lesion for the first time had been described on CT scan of the abdomen in 2010. However, the patient was lost to follow-up. In 2021 CT scan, followed by MRI of the abdomen, perfomed due to reccurent abdominal pain, revealed substantial progression of the tumour size (from 7×5×3 cm in 2010 to 13×10×10 cm in 2021). The patient was qualified for laparotomy. Because of difficult localization and risk of non-radical operation, the lesion was only biopted – the histopathological result was consistent with paraganglioma. Hormonal assessment showed significantly elevated urinary fractionated metanephrines. Genetic testing of SDHB/SDHD, VHL, RET, MEN1, MAX mutation was negative. Control CT scan revealed left hydronephrosis secondary to ureteral obstruction by the tumour mass and further slow progression of the tumour size. Preoperatively performed.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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