ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
Relationship between lipid profile and serum uric acid concentration in patients with type 2 diabetes
Zeineb Zemni 1 , Nesserine Dhieb 1 , Ramla Mizouri 1 , Chaima Sdiri 2 , Maryam Cheikhrouhou 2 , Rym Ben Othman 1 , Nadia Ben Amor 1 , Faten Mahjoub 1 , Berriche Olfa 1 & Jamoussi Henda 1
1National Institute of Nutrition of Tunis, Department A, Bab Saadoun, Tunis, Tunisia; 2National Institute of Nutrition of Tunis, Outpatient Department and Functional Explorations, Bab Saadoun, Tunis, Tunisia
Introduction: hyperuricemia is a marker of cardiovascular risk. The aim of this study was to examine the relationship between lipid profile and serum uric acid concentration in patients with type 2 diabetes (T2D).
Method: A retrospective study including 100 patients followed in the A department of the National Institute of Nutrition in Tunis. Data were collected from patients’ medical records. The lipid profile includes low density lipoprotein (LDL), high density lipoprotein (HDL), non high density lipoprotein (non-HDL), triglyceride (TG) and total cholesterol (TC). Hyperuricemia was defined as serum uric acid greater than 6 mg/dl (360 µmol/l).
Results: The mean age of patients was 56.75±12 years ,48% were men and 52% were women. The average duration of diabetes was 8.27±6 years. The mean body mass index (BMI) was 29.55±4.33 kg/m2. Almost one third of the patients (29%) had hyperuricemia (with no clinical manifestations of gout) and 64.5% had dyslipidemia. We found a positive and statistically significant correlation between TG and uric acid level (r=0.45, P0.002). Non-HDL cholesterol was positively correlated with uric acid levels and trend to significance (r=0.28, P0.052). There was no correlation between LDL, HDL and uric acid concentration.
Conclusion: The results of our study illustrate the strong association between uric acid increase and lipid disorder in patients with T2D suggesting a crucial role of uric acid in the regulation of dyslipidemia.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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