ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)
A simple score for predicting non-alcoholic fatty liver disease in obese patients
Meriam Dalhoum 1 , Berriche Olfa 1 , Riahi Sameh 2 , Hamza Sahar 2 , Tlili Raja 2 , Amel Gamoudi 1 , Rym Ben Othman 1 , Nadia Ben Amor 1 , Ramla Mizouri 1 , Awatef Kacem 1 , Kallel Lamia 2 & Jamoussi Henda 1
1National Institute of Nutrition in Tunis, Human Obesity Research Unit, Tunis, Tunisia; 2Mahmoud El Matri Hospital, Ariana, Gastroenterology Department, Tunis, Tunisia
Introduction: Non-alcoholic fatty liver disease (NAFLD) represents the most common and fastest growing liver disease. Its incidence is associated with the global obesity epidemic.
Objective: To develop a simple score to predict the risk of NAFLD in the obese patient.
Methods and Materials: This is a descriptive cross-sectional study including 95 patients who consulted at the Human Obesity Research Unit of the National Institute of Nutrition in Tunis. Patients were interviewed, anthropometric measurements (weight, height, body mass index (BMI), waist circumference) were taken, biological assessment (fasting blood glucose, triglyceride, total cholesterol, HDL-cholesterol) and abdominal ultrasound were conducted to look for hepatic steatosis.
Results: The mean age of our patients was 48.7±7 years with a female predominance (91.6%). The mean BMI was 41±13 kg/m2. The mean waist circumference was 114±8 cm. The frequency of hepatic steatosis was 70.5%. In univariate analysis, the following NAFLD risk factors: BMI, waist circumference, waist-to-height ratio ≥0.7 and triglyceride/HDL cholesterol ratio ≥2.5 were all correlated with hepatic steatosis with a statistically positive P (P<0.05). In multivariate analysis, only waist-to-height ratio ≥0.7 was independently associated with NAFLD with an adjusted Odds Ratio of 4.1 (P=0.03).
Conclusion: Waist-to-height ratio ≥0.7 is an independent risk factor for NAFLD in obese patients. It is a simple parameter that can be used in routine practice as a screening tool for non-alcoholic fatty liver disease.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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