Endocrine Abstracts

Introduction: Depression often occurs as comorbid and concomitant disorder in patients with type 2 diabetes (T2D) complicating the course and outcome of the disease, prolonging the treatment and accelerating complications of diabetes, especialy cardiovascular complications. Numerous researches show significant presence of cardiovascular disorders in depressed patients with T2D that show up several year after first depressive episode. Mortality caused by cardiovascular disorders in depressed patients with T2D is 50% higher than in general population. Comorbid depression and cardiovascular disorders in diabetic patients making worse health condition, increasing suffering, making hard treatment and outcome is not good.

Aim: The goal is to confirm presence of cardiovascular disorders in depressed patients with T2D as the most common comorbid cardiovasvular diseases.

Methods: A retrospective study has been conducted using data from medical history of 274 depressed patients with T2D hospitalized and treated at the Psychiatric Clinic, University Clinical Center of Republic of Srpska. These parameters were assessed: sex, age, number of hospitalizations, marital and employer status, comorbid disease, body mass index, presence of cardiovascular disorders and laboratory tests (glycemia, lipid status and renal function parameters). Data were presented using tables and graphs.

Results: Cardiovascular disorders in patients with T2D comorbidity with depression we found in 126 patients (45.9%), 96 of them were males and 30 females. Hypertension in comorbidity with depression in diabetic patients was diagnosed in 83 patients (65.8%), while comorbid with cardiac disordes was found in 45 patients (35.7%). In the group of depressive diabetics patients with cardiovascular disorders, 65% of them had unsatisfactory level of glycoregulation.

Conclusion: Depression is often accompained by cardiovascular disorders in patients with T2D. It is very important to recognize this comorbidity in order to treat it successfully and to make better treatment’s otucome.

Keywords: diabetes mellitus type 2, depression, cardiovascular disorders.