Endocrine Abstracts

Objective: Adrenal venous sampling (AVS) is a reliable procedure to differentiate if in patients with primary aldosteronism (PA) aldosterone production is unilateral or bilateral and guide treatment of these patients. Our objective was to describe their characteristics and the outcomes of the AVS.

Methods and patients: Observational longitudinal clinical study between July 2020 and November 2022 in patients who underwent AVS in our Hospital.

Results: 21 patients included. 24 AVPs performed. Mean age: 56.1±12.66 years. 52.4% women. Reason of PA screening: 38.1% resistant high blood pressure (HBP), 23.8% HBP and adrenal adenoma and 38.1% HPA and hypokalemia. 90.5% patients with an adenoma in the CT: 28.6% in the right gland, 57.1% in the left and 4.8% in both. 9.5% of patients without adenoma in CT. 70.8% of catheterization of both adrenal glands was successful.35.3% with no lateralization. Among the 11 successful AVS with lateralization, in 9 of them AVS lateralization matched the image. In 1 patient AVS lateralized to the opposite side. In 1 patient AVS showed left lateralization although no adenoma was seen in CT. 29.2% unsuccessful AVS: Most of them (85.7%) because of inadequate right adrenal vein catheterization.

Conclusion: – In spite of the limited number of AVS performed in our center, AVS is successful in most of the patients in our series. As previously described, inadequate right adrenal vein catheterization is the main cause of unsuccessful AVS.– In most patients AVS lateralization results matched the side of the adenoma in the CT image if it was present.