Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2022) 86 P27 | DOI: 10.1530/endoabs.86.P27

SFEBES2022 Poster Presentations Adrenal and Cardiovascular (66 abstracts)

Sulfasalazine as a cause of false positive elevation of normetanephrine in patients with adrenal mass – A diagnostic challenge

Eunice Ter Zuling & Sabapathy Balasubramanian


Northern General Hospital, Sheffield, United Kingdom


In clinical settings, when biochemical screening revealed grossly elevated urinary normetanephrine and metanephrine in the presence of an adrenal mass, there is a high clinical suspicion of a pheochromocytoma. However, sulfasalazine, an anti-inflammatory drug can cause analytical drug interference, leading to falsely positive elevation of urinary normetanephrine and a misdiagnosis of phantom pheochromocytoma. This report illustrates two patients with adrenal mass who had false positive elevation of normetanephrine due to sulfasalazine, one of whom underwent adrenalectomy and another one did not.

Volume 86

Society for Endocrinology BES 2022

Harrogate, United Kingdom
14 Nov 2022 - 16 Nov 2022

Society for Endocrinology 

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