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Endocrine Abstracts (2022) 83 TO5 | DOI: 10.1530/endoabs.83.TO5

EYES2022 ESE Young Endocrinologists and Scientists (EYES) 2022 Thyroid (12 abstracts)

Is our recommendation to quit smoking considered in patients with Graves’ Disease and Graves’ Orbitopathy?

Coskun M 1 , Bektas Y 2 , Yetimoglu N 2 , Yalcin M. M. 1 , Tarlan B 3 , Konuk O 3 , Balos Toruner F 1 & Ayvaz G 4


1Gazi University Faculty of Medicine: Gazi Universitesi Tip Fakultesi, Department of Endocrinology and Metabolism; 2Gazi University Faculty of Medicine: Gazi Universitesi Tip Fakultesi, Department of Medical School; 3Gazi University Faculty of Medicine: Gazi Universitesi Tip Fakultesi, Department of Ophthalmology; 4Koru Hospital, Department of Endocrinology and Metabolism


Background and Objective: Smoking increases the risk of Graves’ orbitopathy (GO) in patients with Graves’ disease (GD). Therefore, smoking cessation should be recommended to all patients with GD. This study aimed to investigate whether smoking cessation recommendations were taken into account in patients with GD and whether there was a difference in terms of smoking cessation between those with and without GO.

Methods: Smoking status of the cases followed up with GD, who were active smokers when diagnosed, were questioned by telephone visit. The relationship of these data with the presence of GO was evaluated.

Results: 74 smokers with GD were included in the study. The mean age of the patients was 48.0 ±10.9 years, and 62.2% were women. All patients were advised to quit smoking by their physicians. While the number of cigarettes was 20 (10-22)/day at the first visit, the current cigarette use was 7 (0-15)/day, (P < 0.001). Forty-nine (66.2%) of the patients had GO. It was found that 49% of patients with GO and 36% of those with non-GO quit smoking (p:0.08). The decrease in number of cigarettes/day after the physician’s recommendation was significantly higher in patients with GO than patients with non-GO (-95.4% vs. -54.5%), (P = 0.02).

Conclusion: Although the importance of smoke cessation was emphasized in all patients with GD, we observed that smoking cessation advice was more followed in the GO group in our study. Explaining in detail that smoking in GD may worsen the course of the disease and impair the quality of life in the possible development of GO, may lead patients to consider smoking cessation recommendations more.

Keywords: Graves disease, Graves orbitopathy, smoking, cigarette, smoke cessation

Volume 83

ESE Young Endocrinologists and Scientists (EYES) 2022

Zagreb, Croatia
02 Sep 2022 - 04 Sep 2022

European Society of Endocrinology 

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