ECE2022 Eposter Presentations Pituitary and Neuroendocrinology (211 abstracts)
Visual impairment in the empty sella syndrome
Mnif Fatma , Asma Zargni , Kawthar El Arbi , Faten Haj Kacem Akid , Dhoha Ben Salah , Nadia Charfi , Mouna Mnif , Nabila Rekik Majdoub , Mouna Elleuch & Mohamed Abid
Hedi Chaker Hospital, Diabetology and Endocrinology Department, Sfax, Tunisia
Introduction: Empty sella syndrome (ESS) is a rare condition in which the sella turcica is partially or completely filled with cerebrospinal fluid. It can be primary or secondary. Ophthalmologic involvement is rare in primary empty sella Syndrome. It is described in only 1.6 to 16% of cases.
Patients and methods: We report a retrospective study of 46 cases of ESS collected in the endocrinology department over the period from 1991 to 2020. The clinical and biochemical profile of ESS patients were analyzed.
Results: We included 46 patients, with a mean age of 50.4 years (with extremes from 21 to 81 years), with a female predominance (75%). The average parity was 9.5 children per woman. The circumstances of discovery were dominated by headaches (66.67%). Obesity was noted in 19.45% of cases. The hormonal assessment showed a corticotropic deficiency (53.6%), a thyrotropic deficiency (36.11%), a gonadotropic deficiency (22.8%) and diabetes insipidus in 2 patients. Hyperprolactinemia was noted in 13.88% of cases. Visual impairment was noted in 30.56% of cases (11 patients). two patients had diplopia. A decline in visual acuity was present in 2 cases. Visual blur was described in 7 cases. Hormone deficiency replacement was prescribed. The evolution was marked by the persistence of visual disorders in 8 patients.
Discussion: ESS is a benign pathology provided that antehypophyseal insufficiency is detected. We underline the interest of a systematic ophthalmologic examination in patients with ESS in order to detect visual disorders which can be serious and threaten the visual prognosis.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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