Endocrine Abstracts

The purpose of the study is to assess the quality of life of patients with autoimmune polyglandular type 2 syndrome using the questionnaire.

Material and research methods: Under our observation there were the following 2 groups of patients: 1 gr. - patients with APS with AIT (primary adrenal insufficiency and autoimmune thyroiditis) - 25 patients, 2 gr. - APS with DM 1 (type 1 diabetes mellitus type 1 - 30 patients, as well as 20 healthy persons of the appropriate age and gender. The study used generally crystal and clinical and biochemical methods of research, hormonal blood tests (TSH, free thyroxine, antibodies to TPO, cortisol), immunological studies (antibodies to thyroid gland, to the pancreas, to adrenal glands), and instrumental research methods (ECG, ultrasound of internal organs, thyroid gland, genital organs, neurophthalmologic, radiographic - MSCT of adrenal glands, statistical techniques, as well as the quality of life of patients with ADDIQOL. AddoQol consists of 30 questions with the estimate of each question in 6 points. At the same time, the patient must be selected in each question 1 answer: ‘Yes’ or ‘no’. If the patient is gaining more than 15 points with the answer ‘Yes’, then this indicates a low quality of life [1].

Research results: The assessment of the quality of life (QoL) on the AddOQOL questionnaire showed that the middle score of patients 1 of the group was 18 ± 0.95, and in healthy - 2.35 ± 0.54 (P<0.05). The average score in patients 2 groups amounted to 19.6 ± 1.06 (P<0.05).

Conclusions: QoL patients in patients with APS 2 type of both groups has significantly lagging behind QoL in healthy faces.