ECE2022 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (318 abstracts)
Cardio-metabolic profile of morbid obesity compared to moderate and severe obesity
Zeineb Zemni 1 , Emna Bornaz 1 , Nadia Alaya 2 , Olfa Lajili 1 , Rihab Yamoun 2 , Eya Safi 3 , Ben Ali Khaoula 3 , Nadia Ben Amor 1 , Ramla Mizouri 1 , Ryme Ben Othman 1 , olfa Berriche 1 , Faten Mahjoub 1 & Henda Jamoussi 1
1National Institute of Nutrition of Tunis, The Unit of Obesity Research, Tunisia; 2National Institute of Nutrition of Tunis, Outpatient Department and Functional Explorations, Tunis, Tunisia; 3Military Hospital of Instruction of Tunis, Endocrinology Department, Tunis, Tunisia
Introduction: Obesity is the disease of modern society whose prevalence continues to increase.
The aim of this study was to compare the cardio-metabolic profile of morbid obesity with that of moderate to severe obesity.
Methods: It was a retrospective study conducted at the obesity unit of the national institute of nutrition in Tunis including 174 obese patients We divided the population into two groups. Group 1 (G1) with morbid obesity including 83 patients and group 2 (G2) with moderate to severe obesity including 91 patients. Morbid obesity is defined by a BMI ≥ 40 kg/m2 and moderate to severe obesity is defined by a BMI between 30-39.9 kg/m2. Clinical and biological data were collected from medical observation records.
Results: The mean age of our patients was 42.22 years in G1 and 47.93 years in G2 (P=0.006). A female predominance was noted in both groups, sex ratio M/F (G1): 0.18 and (G2): 049. A significant association was found between female gender and morbid obesity (P=0.008). The study of the metabolic profile did not find any significant difference in the prevalence of diabetes between the two groups but dyslipidemia was higher in G2 (P=0.024). The mean waist circumference was higher in the morbidly obese group (127.7 cm VS 114.99 cm) (P<0.001). No significant difference was found between the biological parameters of the two groups. Regarding cardiovascular complications, there was no significant difference between the two groups in the prevalence of heart failure, hypertension, and stroke. Joint complications such as gonalgia and low back pain were higher in G1 (P=0.015). Sedentary lifestyle was higher in the morbidly obese group (69.88% vs. 51.65%) with a significant difference between the two groups (P=0.014). The prevalence of eating disorders (the presence of at least one disorder) was higher in G1 (89.16% vs 74.73%) (P=0.014).
Conclusion: Our study showed that despite higher body fat, morbid obesity is not characterized by a more severe cardio-metabolic profile compared to moderate and severe obesity.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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