Endocrine Abstracts

Background: Over the last year the social consequences of obesity has become significant, with weight-based stigmatization and prejudiced common outcomes. Toxic hepatitis is one of those diseases that has obese as comorbidity in different age groups. The pervasiveness of prejudice toward obese in patients with toxic hepatitis makes it imperative that scientists have access to valid and reliable measures to assess weight bias.

Objectives: Age groups structuring and examination of patients with toxic hepatitis for obesity detection as one of the hepatic fibrogenesis triggers. Methods124 patients with toxic liver disease were examined. The body mass index (BMI, Kettle index) was calculated using anthropometric indicators. For all our patients BMI was interpreted using standard weight status categories (classification of BMI adopted by the WHO (1997). The value of BMI in the range of 18.5-24.9 kg/m² should be considered optimal - normal or healthy weight; reduced BMI or underweight ≥ 18.5; overweight - 25.0-29.9; obesity I degree - 30,0-34,9; obesity II degree - 35,0-39,9; grade III obesity - ≥ 40 (kg/m²). The age standards were interpreted using adopted by the WHO/Europe, according to which the young age is 25-44, the average age - 44-60, the older age - 60-75, the elderly age - 75-90, people aged 90 and over considered as long-lived. However, it should be noted that the last age category among the examined patients was not presented.

Results: The examination revealed that the following changes were observed in BMI: 52.8% of patients were with normal weight, 39% were overweight, obesity I degree was detected in 8.1% of patients. Age structuring of BMI is given in the table.

Conclusions: Obesity of varying degrees was found in 47.2% of patients with toxic hepatitis in all age groups. The most numerous was group of average age (n = 56), the smallest in number was group of old age patients (n = 7). These data should be taken into account when choosing and prescribing adequate treatment, nutrition should always be considered among physicians in the liver and obesity fields, who have an important role to play in improving the quality of life for so many individuals afected by these pathologies.