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Endocrine Abstracts (2022) 81 EP1127 | DOI: 10.1530/endoabs.81.EP1127

ENT Department Farhat Hached Hospital Sousse, Sousse, Tunisia


The goal of this study is to examine the role of surgery in the treatment of Graves’ disease and to assess the surgical outcomes.

Methods: We present the results of a retrospective analysis of 31 Graves’ disease cases operated on in the ENT and cervico-facial surgery departments of Farhat Hached Sousse Hospital during a six-year period [2015-2021]. Our group consisted of 05 males and 26 women. The average age ranged from 12 to 70 years. Between diagnosis and operation, the average period was 35.6 months [06-120 months]. A homogenous goiter (93.5%) and a thyroid of normal volume were discovered during a cervical examination (6.5 percent). TSH and FT4 levels were 14.42 pmol/l and 1.12 mU/l, respectively, at the median. When faced with: resistance to medical therapy (77.4%), existence of compression signals (9.7%), presence of thyroid nodules (6.5%), severe ophthalmopathy (3.2%), and patient desire, surgery was recommended (3.2 percent). In all of the patients, a complete thyroidectomy was performed. Following surgery, one patient experienced brief recurring paralysis. Hypocalcemia was discovered in 38.7% of the patients. In any event, it was only temporary. After surgery, no patient experienced an acute thyrotoxic crisis. A histological investigation revealed Graves’ disease, but no evidence of cancer. The average period of follow-up was three years.

Conclusion: Graves’ disease is a thyroid autoimmune illness. Because of the disease’s evolutionary vagaries, treating it is tough. Medical therapy has been related to repeated recurrences and a variety of side effects, all of which have a negative impact on these patients’ quality of life. Surgery based on total thyroidectomy represents a safe alternative with a low rate of complications.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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