Searchable abstracts of presentations at key conferences in endocrinology
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European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

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The 24th European Congress of Endocrinology (ECE) and the Italian Society of Endocrinology look forward to welcoming you to Milan. ECE 2022 returns for a four day, six parallel session festival of endocrine science. You can join us In person in Milan, Italy OR Live @Home online!

Symposia

Genetic and epigenetic basis of PCOS heritability

ea0081s2.1 | Genetic and epigenetic basis of PCOS heritability | ECE2022

Prenatal androgen exposure causes transgenerational epigenetic transmission of PCOS

Stener-Victorin Elisabet

In a register-based and case-control studies it has been shown that daughters of women with or without PCOS have a five-fold increased risk of being diagnosed with the syndrom. Moreover, sons born to a mother with PCOS have two to three-fold increased risk of being obese. But how PCOS is inherited is unclear as PCOS loci identified by genome-wide association studies account for only 10% of the heritability. It has been suggested that epigenetic and developmental programming co...