Endocrine Abstracts

Thyroid hormones (TH) regulate (brain) development, growth, body temperature, most pathways involved in energy and structural metabolism as well as anabolic and catabolic reactions. Inadequate availability of essential trace elements (iodine, selenium, iron, zinc) limits TH biosynthesis, metabolism and action. Endocrine-disrupting chemicals (EDC), i.e., exogenous chemicals or their mixtures, can interfere with any aspect of TH synthesis, distribution, transport, metabolism, an...

Unfortunately diabetes is a growing problem with now more than 537 million people worldwide having diabetes according to International Diabetes Federation. Excess morbidity and mortality in diabetes is related to the development of diabetic kidney disease seen in 30-40%, which not only causes end stage kidney disease, but also increases risk for cardiovascular events and mortality, which is the leading cause of death. Treatment of diabetic kidney disease has been control of gl...