ECE2022 Poster Presentations Late-Breaking (41 abstracts)
Retrospective assessment of malignant thyroid nodules in a group of children and adolescents according to BTA U classification and ACR TI-RADS ultrasound-based risk stratification system in combination with elastography
Artur Bossowski , Hanna Borysewicz-Sanczyk , Beata Sawicka , Filip Bossowski , Agata Karny , Aleksandra Rusak & Janusz Dzieciol
Medical University in Bialystok, Dep of Pediatric Endocrinology and Diabetes, with a Cardiology Division., Białystok, Poland
The risk of malignancy in thyroid nodules correlates with the presence of ultrasound features. In adults, ultrasound risk-classification systems have been proposed to indicate the need for further invasive diagnosis. Furthermore, elastography has been shown to support differential diagnosis of thyroid nodules. The purpose of our study was to assess the application of the American Thyroid Association (ATA) and British Thyroid Association (BTA) ultrasound risk-classification systems as well as strain elastography in the management of thyroid nodules in children and adolescents. Seventeen nodules with Bethesda III, IV, V and VI were selected from 165 focal lesions in children. All patients underwent ultrasonography and elastography followed by fine needle aspiration biopsy. Ultrasound the ATA and BTA stratification systems were assessed retrospectively. The strain ratio in the group of thyroid nodules diagnosed as malignant was significantly higher than in benign nodules (6.07 vs. 3.09, P=0.036). According to the ATA guidelines, 100% of malignant nodules were classified as high suspicion and 73% of benign nodules were assessed as low suspicion. Using the BTA U-score classification, 80% of malignant nodules were classified as cancerous (U5) and 20% as suspicious for malignancy (U4). Among benign nodules, 82% were classified as indeterminate or equivocal (U3) and 9% as benign (U2). Our results suggest that application of the ATA or BTA stratification system together with elastography may improve differential diagnosis and help make a clinical decision about the need for further invasive diagnosis of thyroid nodules in children.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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