ECE2022 Eposter Presentations Thyroid (219 abstracts)
Use of thyroid hormone in hypothyroid and euthyroid patients. the THESIS questionnaire survey in spain
Juan Carlos Galofré 1 , Roberto Attanasio 2 , Laszlo Hegedüs 3 , Endre V. Nagy 4 , Roberto Negro 5 , Enrico Papini 6 , Petros Perros 7 & Juan Jose Diez 8
1Clínica Universidad de Navarra, Endocrinology, Pamplona, Spain; 2IRCCS Orthopedic Institute Galeazzi, Endocrine Unit, Milan, Italy; 3Odense University Hospital, Endocrinology and Metabolism, Odense, Denmark; 4Department of Medicine, Faculty of Medicine, University of Debrecen, Division of Endocrinology, Debrecen, Hungary; 5V. Fazzi Hospital, Division of Endocrinology, Lecce, Italy; 6Regina Apostolorum Hospital, Department of Endocrinology and Metabolism, Rome, Italy; 7Royal Victoria Infirmary, Department of Endocrinology, Newcastle upon Tyne, United Kingdom; 8Hospital Universitario Puerta de Hierro, Department of Endocrinology, Madrid, Spain
Background: Hypothyroidism is one of the most frequent conditions in endocrinology. Despite of that fact, indications for treatment differ among specialists in Spain.
Aims: To identify attitudes of Spanish endocrinologists in the use of levothyroxine (LT4) therapy and the management of hypothyroidism.
Methods: The members of the Sociedad Española de Endocrinología y Nutrición (Spanish Society of Endocrinology and Nutrition) were requested to participate in a web-based survey. The questionnaire, conducted between September and November 2020, was adapted in accordance with the availability of thyroid hormone formulations in Spain.
Results: A total of 512 of 1956 (25.8%) members (66% female) completed the survey; 97.4% affirmed that LT4 is the initial treatment for hypothyroidism. The indications for LT4 therapy in euthyroidism were infertility in thyroid antibody positive women (48.5%) and simple goitre (21.2%). However, 44.2% of endocrinologists reported that there was no such indication for these patients. Only a minority of interviewees (2.6%) considered combining LT4 with liothyronine as the treatment of choice at diagnosis whereas 49% stated that it should never be used.
Conclusions: The standard of treatment of hypothyroidism in Spain is almost exclusively with LT4 tablets. Availability of other formulations of LT4 or combination therapy for hypothyroidism management remains to be explored specially in patients with persistent symptoms. Remarkably, non-evidence based use of LT4 is extensively practiced in Spain for euthyroid women with autoimmune thyroiditis and fertility problems.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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