ECE2022 Eposter Presentations Thyroid (219 abstracts)
Case report: Amiodarone-induced thyroid dysfunction
Faten Haj Kacem Akid , Oumeyma Trimeche , AbdelMouhaymen Missaoui , Dhoha Ben Salah , Mnif Fatma , Nadia Charfi , Mouna Mnif , NABILA REKIK MAJDOUB , Mouna Elleuch & Mohamed Abid
Hedi Chaker Hospital, Endocrinology, Sfax, Tunisia
Amiodarone is considered by many the most potent antiarrhythmic drug. The other side of the coin is that it’s associated with many side effects including disturbances in the thyroid function, which can be seen in 14 to 18 % of the cases (1). This case is about a 56-year-old male patient with a history of mitral valve disease who was on Amiodarone for 3 years. His personal history was notable with Epilepsy of unknow etiology for which he was on sodium valproate. During follow-up, the thyroid function was assessed twice at a 1-month interval and results were consisting with a patent hyperthyroidism. One month later, the patient was referred for our endocrine department and lab work revealed this time hypothyroidism. Thus, the patient was treated with levothyroxine. This case highlights the effects of Amiodarone on the thyroid gland and demonstrate the possible spontaneous evolution of amiodarone induced thyrotoxicosis into hypothyroidism.
References: 1. Martino E, Bartalena L, Bogazzi F, Braverman LE. The Effects of Amiodarone on the Thyroid*. Endocr Rev. 1 avr 2001;22(2):240–54.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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