Endocrine Abstracts

The goal of this study is to examine the role of surgery in the treatment of Graves’ disease and to assess the surgical outcomes.

Methods: We present the results of a retrospective analysis of 31 Graves’ disease cases operated on in the ENT and cervico-facial surgery departments of Farhat Hached Sousse Hospital during a six-year period [2015-2021]. Our group consisted of 05 males and 26 women. The average age ranged from 12 to 70 years. Between diagnosis and operation, the average period was 35.6 months [06-120 months]. A homogenous goiter (93.5%) and a thyroid of normal volume were discovered during a cervical examination (6.5 percent). TSH and FT4 levels were 14.42 pmol/l and 1.12 mU/l, respectively, at the median. When faced with: resistance to medical therapy (77.4%), existence of compression signals (9.7%), presence of thyroid nodules (6.5%), severe ophthalmopathy (3.2%), and patient desire, surgery was recommended (3.2 percent). In all of the patients, a complete thyroidectomy was performed. Following surgery, one patient experienced brief recurring paralysis. Hypocalcemia was discovered in 38.7% of the patients. In any event, it was only temporary. After surgery, no patient experienced an acute thyrotoxic crisis. A histological investigation revealed Graves’ disease, but no evidence of cancer. The average period of follow-up was three years.

Conclusion: Graves’ disease is a thyroid autoimmune illness. Because of the disease’s evolutionary vagaries, treating it is tough. Medical therapy has been related to repeated recurrences and a variety of side effects, all of which have a negative impact on these patients’ quality of life. Surgery based on total thyroidectomy represents a safe alternative with a low rate of complications.