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Endocrine Abstracts (2022) 81 EP1120 | DOI: 10.1530/endoabs.81.EP1120

Fattouma Bourguiba University Hospital, ENT and Head and Neck Surgery Department, Monastir, Tunisia


Introduction: Total thyroidectomy is the most common surgical procedure for the treatment of thyroid diseases. Postoperative hypoparathyroidism and the resulting hypocalcemia are frequent complications after total thyroidectomy. The aim of this study was to assess the rate of postoperative hypoparathyroidism after total thyroidectomy in order to identify potential risk factors.

Methods: We designed a retrospective study including 387 patients with total thyroidectomy who were operated in our department from January 2016 to January 2019. The prevalence of hypoparathyroidism was evaluated at day 3, 1 month, 6 months and 12 months after surgery.

Results: The average age of our patients was 46.9 years old; 16.7% were males and 83.3 % were females. The total thyroidectomy was done in 210 (54.2 %) of cases for a malignant pathology. A total of 189 patients (48.83%) underwent a neck dissection. 90 (23.2 %) developed postoperative hypoparathyroidism at day 3. Most of them recover parathyroid function over time. Prevalence of hypoparathyroidism at 1 month, 6months and 12 months was 9%, 4% and 2.8 %, respectively. The risk of developing definitive hypoparathyroidism was related to the presence of parathyroid tissue at histology, concomitant central lymph node dissection and incidental para thyroidectomy without auto transplantation.

Conclusion: Although most patients with postsurgical hypoparathyroidism recover parathyroid function, intra-operative preservation of the parathyroid glands is the best prophylaxis to avoid postoperative hypoparathyroidism after total thyroidectomy.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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