Endocrine Abstracts

Background: Several studies have demonstrated the relationship between breast cancer and thyroid cancer by the presence of common genetic determinants. The aim of the study was to define the breast cancer prevalence among patients followed for thyroid carcinoma and to determine factors favoring this association.

Matherials and methods: A Cross-sectional study was conducted in the Ibn Rochd University Hospital Endocrinology and Diabetology department of Casablanca, including 55 patients followed for thyroid carcinoma between 1986- 2021 among all the thyroid differentiated carcinomas (793 patients) and presenting breast cancer. Statistical analysis performed by the software SPSS 25.0

Results: Prevalence of patients presenting breast cancer and thyroid cancer was 6.3%. Mean age was 45.5 years (36-70). Family history of neoplasia was found in 49.1% of cases. Breast cancer preceded the discovery of thyroid cancer in 51% of cases. Iratherapy was performed in 98.2% of patients. External radiotherapy was realized in 45.4% of cases for the treatment of breast cancer papillary carcinoma and invasive ductal carcinoma were the predominant histological type in 89.1% of cases. Predictor factors of this association were female patients who had the first neoplasia at a young age (≤45years), family history of neoplasia and prior external radiotherapy.

Conclusion: Our study results support the hypothesis of the presence of a relationship between the breast cancer occurrence in patients followed for thyroid cancer. Close monitoring and vigilance for early detection of thyroid cancer in patients treated for breast cancer is recommended.