Endocrine Abstracts

Introduction: Epidemiological studies have reported that being overweight and being obese are associated with increased incidences of numerous cancers, including thyroid cancer. In addition to cancer risk, obesity has also been demonstrated to be associated with more aggressive pathological characteristics of the tumor and worse prognosis in patients with several cancers.

Purpose of study: Demonstrate the relationships between BMI and the clinico-pathological features of papillary thyroid carcinoma.

Materials and methods: Retrospective study was conducted in the Ibn Rochd University Hospital Endocrinology and Diabetology department of Casablanca, including211 patients followed for papillary thyroid carcinoma between August 2018 and January 2022. The patients were divided into 2 groups: a group with obesity, and a control group, comparing the clinico-pathological characteristics of the two groups. Statistical analysis performed by the software SPSS 25.0

Results: According to the results, 377patients were women (90.8%), mean age was 40.4 years (12-86) and mean BMI was 28.9 kg/m²(21-45). The mean tumor size was 28.6 mm (1-80). Statistical analysis of the prognostic factors: tumor size, multifocality, presence of vascular emboli and distant metastasis showed no significant differences in the obese group compared to the control group. Only the presence of capsular invasion (P<0.01) was strongly associated with obesity.

Conclusion: The association between obesity and carcinoma has been widely elucidated. Our study demonstrated that there is no relationship of BMI and clinico-pathological features of thyroid carcinoma such as multifocality, tumor size, vascular invasion and the presence of lymph node metastases apart from the presence of capsular invasion.