ECE2022 Eposter Presentations Thyroid (219 abstracts)
Tahar Sfar Hospital, Mahdia, Otorhinolaryngology, Tunisia
Introduction: Thyroid carcinoma in Graves disease is rare (1 to 2%). Papillary carcinoma is the most common histologic type. It is usually discovered incidentally after histologic exam. Our aim is to report a case of Graves disease associated with thyroid papillary carcinoma and to describe its therapeutic and prognostic features.
Case report: A 51-year-old woman treated with anti-thyroid drugs and β blockers for Graves disease. Cervical ultrasound found an enlarged, hypervascular thyroid gland with a 10 mm nodule classified EUTIRADS 5. Indication for surgery was: failed medical therapy after 3 years of treatment and concomitant suspicious thyroid nodule. The patient underwent total thyroidectomy. Intraoperative examination suggested a papillary thyroid carcinoma. So, a central neck dissection was performed. Histologic exam confirmed the diagnosis of papillary thyroid carcinoma associated with Graves disease. The patient underwent ablative radioiodine therapy. After 7 years of follow-up, she had no recurrence.
Conclusion: Patients with Graves disease had a higher risk of developing thyroid cancer than the general population. However, studies reported conflicting results about the prognosis of thyroid cancer concomitant with graves disease.