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Endocrine Abstracts (2022) 81 EP1042 | DOI: 10.1530/endoabs.81.EP1042

Tahar Sfar Hospital, Mahdia, Otorhinolaryngology, Tunisia


Introduction: Thyroid carcinoma in Graves’ disease is rare (1 to 2%). Papillary carcinoma is the most common histologic type. It is usually discovered incidentally after histologic exam. Our aim is to report a case of Graves’ disease associated with thyroid papillary carcinoma and to describe its therapeutic and prognostic features.

Case report: A 51-year-old woman treated with anti-thyroid drugs and β blockers for Graves’ disease. Cervical ultrasound found an enlarged, hypervascular thyroid gland with a 10 mm nodule classified EUTIRADS 5. Indication for surgery was: failed medical therapy after 3 years of treatment and concomitant suspicious thyroid nodule. The patient underwent total thyroidectomy. Intraoperative examination suggested a papillary thyroid carcinoma. So, a central neck dissection was performed. Histologic exam confirmed the diagnosis of papillary thyroid carcinoma associated with Graves’ disease. The patient underwent ablative radioiodine therapy. After 7 years of follow-up, she had no recurrence.

Conclusion: Patients with Graves’ disease had a higher risk of developing thyroid cancer than the general population. However, studies reported conflicting results about the prognosis of thyroid cancer concomitant with graves’ disease.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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