ECE2022 Eposter Presentations Thyroid (219 abstracts)
Diagnosis and management of anaplastic thyroid carcinoma: about 3 cases and review of literrature
Rachida Bouattay , Emna Bergaoui , Maroua Naouar , Mehdi Ferjaoui , Heyfa Belhadjmiled , Amel Elkorbi , Kaled Harrathi , Naourez Kolsi & Jamel Koubaa
Fattouma Bourguiba Hospital, ENT, Monastir, Tunisia
Introduction: Anaplasic thyroid carcinoma is an extremely aggressive undifferentiated tumor of follicular cell origin. It is uncommon and comprising approximately 1% of all thyroid cancers.
Purpose of the presentation: The objective of this work is to determine the clinical, histological and therapeutic aspects of anaplasic thyroid carcinoma.
Methods: This is a retrospective study about 4 patients treated for an anaplasic thyroid carcinoma, in the ENT department of Fattouma Bourguiba hospital in Monastir over a period of 22 years (2000-2021).
Results: The average age was 68 years. A female predominance was noted. The average consultation time was 2 months. Patients consulted for a rapidly progressive goitre in all cases, associated with dysphagia and dyspnea in 3 cases (75%). Cervical examination showed a painful and indurated anterior cervical swelling with a medium size of 5 cm in all patients. Associated lymph nodes were found in 2 cases (50%). Indirect laryngoscopy showed laryngeal paralysis in 2patients (50%), one of which was bilateral (25%). Cervical ultrasound and cervico-thoracic scan showed a mass pushing back the trachea in three cases (75%). 3 patients (75%) had an emergency tracheostomy with thyroid biopsy. The other patient underwent a lobo-isthmectomy. Radiotherapy was indicated in all cases. The evolution was fatal in all patients with a survival of less than 6months.
Conclusion: Anaplastic thyroid cancer is a very rare case and has a poor prognosis. The important information such as clinical manifestations, physical examination and imaging are necessary to diagnose and administer the proper management.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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