ECE2022 Eposter Presentations Pituitary and Neuroendocrinology (211 abstracts)
Metabolic abnormalities profile of non-functioning pituitary adenomas
Wahiba Abdellaoui 1 , Imane Assarrar 1 , lamiae zarraa 1 , soumiya berrabeh 1 , Siham Rouf 1 , 2 & Hanane Latrech 1,2
1Mohammed VI University Hospital, Medical School, Mohammed the First University, Department of Endocrinology-Diabetology-Nutrition, OUJDA, Morocco; 2Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, Morocco
Introduction: Metabolic abnormalities are common in pituitary adenomas and metabolic targeting is becoming a new therapeutic approach to the management of most tumor pathologies, especially pituitary tumors. The objective of this work was to assess the metabolic profile of non-functioning pituitary adenomas.
Material and methods: A retrospective and descriptive study, over a period of 6 years, conducted in the Endocrinology-Diabetology and Nutrition department of Oujda in the eastern of Morocco. The study included 24 patients with histologically confirmed non-functional pituitary adenoma.
Results: The mean age was 50±11.2 years, with a female predominance (58.3% of cases). The average duration of the disease was 1.9±3.6 years. The clinical examination found 50% of the patients to be overweight and 20.8% were obese. The metabolic work-up showed type 2 diabetes in 20.8% of cases and pre-diabetes in 33.3%. Hyperuricemia was found in 16.6% of patients. On the lipid panel, mixed dyslipidemia was revealed in 20.8% of the patients, hypertriglyceridemia and hypoHDLemia <0.35 g/l were confirmed respectively in 25% of cases and hypercholesterolemia in 12.5% of patients.
Conclusion: Metabolic abnormalities associated with non-functioning pituitary adenomas are correlated with disease progression and prognosis. The evaluation of metabolic status should be emphasized during treatment of pituitary adenoma and control of metabolic abnormalities should be added to their current therapies.
Bibliography: Metabolic abnormalities in pituitary adenoma patients: a novel therapeuthic target and prognostic factor; YangDiabetes MetabSyndr Obes. 2015; 8: 357361
Article tools
My recent searches
My recently viewed abstracts
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more