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Endocrine Abstracts (2022) 81 EP684 | DOI: 10.1530/endoabs.81.EP684

1Medipol Mega University Hospital, Endocrinology; 2Medipol Mega University Hospital, Internal Medicine, İstanbul, Turkey


Introduction: Rathke Cleft Cysts(RCCs) are benign cysts arising from the remnants of Rathke’s pouch. The most common symptoms are visual field disorders, headache, and pituitary dysfunction.

Case 1: A 26-year-old male was admitted with headache that started 4 days ago. Cranial MRI revealed an appearance mimicking a hemorrhagic adenoma in pituitary. Pituitary hormones were found as normally. Pituitary MRI showed a 12 x 10 x 10 mm hemorrhagic RCCs located in the midline. The patient’s headache disappeared spontaneously within 3 days without the use of any medication. One month and six months later, MRI showed a progressive shrinkage of hemorrhagic RCCs diameters as 4.5 x 5 x 7.5 mm and 3 mm, respectively. In the pituitary MRI taken at the last follow-up 15 months later, it was observed that sequelae remained as a millimetric-thick slit-shaped microcyst in the central gland.

Case 2: A 24-year-old female was admitted with a complaint of headache that started one month ago. The patient, who had a throbbing headache on the right side of her head, was relieved with analgesics. Pituitary MRI revealed a hemorrhagic RCCs with diffusely expanding pituitary gland with a size of 18 x 13 x 8 mm and leveling inside. The patient’s pituitary hormones were checked and no pathological values were found. In the control pituitary MRI one month later, the size of the hemorrhagic RCCs decreased to 8 x 13 x 8 mm.

Conclusion: Patients with hemorrhagic RCCs whose symptoms decreased during close follow-ups and who did not have hormonal disorders were not operated on. The sizes of the masses of the patients who did not develop any complaints or hormonal disorders during their follow-ups decreased.

Key words: Hemorrhagic Rathke Cleft Cysts; Hemorrhagic Adenoma

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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