ECE2022 Eposter Presentations Pituitary and Neuroendocrinology (211 abstracts)
Pituitary adenoma associated with intracavernous meningioma: Case report
Aicha Lachkhem 1 , Abdelkader Yahi 2 , Haffaf Lounes 1 , Benabdelatif Katia 1 , Ahcen Staifi 3 , Hakim Derradji 4 , Elmountassir Ourrad 5 & Ould Kablia Samia 1
1Central Army Hospital, Endocrinology, Algeria; 2Central Army Hospital, Endocrinology, Algiers, Algeria; 3Central Hospital Army, Ophtalmology, Algeria; 4Central Hospital Army, Neurosurgery, Algeria; 5Central Army Hospital, Radiology, Algeria
Introduction: Pituitary adenoma and meningioma are the most benign tumors in the central nervous system (meningioma 35,9%, pituitary tumor: 15,5%). Pituitary adenoma associated with meningioma without a history of radiotherapy is extremely rare.
Case: A 70 years old man operated for post-traumatic subdural hematoma in whom the brain MRI (magnetic resonance imaging) had also shown a macroadenoma, completed with an MRI of the sellar region which were confirmed in the coronal section in T1 weighted image, an iso-intense adenoma taking up gadolinium poorly measuring 16 x 8,5 mm. This adenoma is associated with a right intra-cavernous lesion measuring 11,8 x 8,8 mm presenting intimate contact with the intravenous portion of the internal carotid artery, iso-intense in T1 weighted images and hyper-intense in T2 weighted images which is intensely and homogenously enhanced after injection of gadolinium salts, corresponding to meningioma. Hormonal work-up revealed a serum prolactin level of 1300 ng/ml and a central hypothyroidism. The patient was then started on dopamine agonist (cabergoline 03 mg/week). The response to treatment was excellent, on his MRI follow-up one year after, the adenoma has disappread leaving an arachnoidocele while the meningioma has remained stable. The patient is being followed by Endocrinolgy and Neurosurgery.
Conclusion: The association of meningiomas and pituitary tumors is very rare. If patients who have under- gone previous radiation therapy are excluded from consideration, the presence of these two types of tumors in the same patient becomes even rarer. To our knowledge, the association of an intracavernous meningioma and a prolactinoma in a patient without previous radiation therapy had never been reported.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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