Endocrine Abstracts

Introduction: Nodular thyroid pathology is very frequent. Its exploration requires a clinico-biological evaluation, a cervical ultrasound to look for the ultrasound criteria of malignancy allowing to classify the thyroid nodules according to the EU-TIRADS classification in order to orientate the diagnosis and to indicate the Fine needle aspiration, to finally allow a targeted management. The aim of our study is to investigate the correlation between the EU-TIRADS classification and the Fine-Needle aspiration outcomes.

Materials and Methods: This is a retrospective study including 85 patients with thyroid nodules. Conducted at the Endocrinology, Diabetology and Nutrition Department of the Mohammed VI University Hospital Center of Oujda in MOROCCO.

Results: The average age of our patients was 45 ± 14.1 years with a female predominance of 88%. According to the EU-TIRADS 2017 classification, we noted 2.2% of cases classified as EU-TIRADS2, 35.2% of cases classified as EU-TIRADS3, 49.5% of cases classified as EU-TIRADS 4, and 14.1% of cases classified as EU-TIRADS5. Fine-needle aspiration was performed in 86.9% of cases, 13% of cases came back malignant. The calculated risk of malignancy for each score is 0% for EUTIRADS 2, 9% for EUTIRADS 3, 12% for EUTIRADS 4, 60% for EUTIRADS 5. The EU-TIRADS and Bethesda 2017 correlation had a statistically significant relationship (P= 0.004).

Discussion and Conclusion: The EU-TIRADS system has been prospectively validated and its diagnostic value was confirmed by Yoon et al (1) in a study of 4696 nodules. Compared with other risk stratification systems, the main objective of EU-TIRADS is to provide easy indications to detect thyroid carcinomas with high sensitivity while maintaining high negative predictive value. This, in turn, should reduce unnecessary cytopunctures. In 2017, Russ et al (2) found a correlation between the EU-TIRADS score and the risk of malignancy for each score, and concluded that the risk of malignancy increased with increasing EU-TIRADS score. 1. Yoon JH, Han K, Kim EK, Moon HJ, Kwak JY. Diagnosis and management of small thyroid nodules: A comparative study with six guidelines for thyroid nodules. Radiology. 2017;283(2):560–9. 2. Russ G, Bonnema SJ, Erdogan MF, Durante C, Ngu R, Leenhardt L. European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS. Eur Thyroid J. 2017;6(5):225–37.