ECE2022 Eposter Presentations Late Breaking (59 abstracts)
Mycophenolate mofetil as a treatment for infundibulo-neurohypohysitis related to Gougerot-Sjögren’s syndrome revealed by postpartum diabetes insipidus: A case report
Rachid Smaili 1 , Ikram Raaidi 1 , El Bachiri Soumaya 1 , Lahbib Hafsa 2 & Myriem Bourkia 1
1University Hospital of Tangier, Morocco, Internal Medicine and Clinical Immunology, TANGER, Morocco; 2University Hospital of Tangier, Endocrinology Department, TANGER, Morocco
Infundibulo-neurohypophysitis is an inflammation of the pituitary stalk and posterior gland. It is an autoimmune disease characterized by lymphocytic infiltration of the pituitary gland. It occurs mainly at the end of pregnancy or in the postpartum period, and is related to autoimmune diseases, including autoimmune thyroiditis. But it is rarely related to Gougerot-Sjogren syndrome, which is an autoimmune connective tissue disease with lymphocytic infiltration of the exocrine glands. We report unusual case of a 25-year-old woman with a history of atopic dermatitis who presented in the early postpartum period with central diabetes insipidus and visual hallucination, dry eyes and mouth. Investigation showed a typically imaging of an infundibulo-neurohypophysitis in the pituitary MRI, associated with a primary Gougerot-Sjogren’s syndrome confirmed at the salivary gland biopsy. Patient was treated with mycophenolate mofetil at 1 gramme by day, and desmopressin replacement therapy with a good clinical and radiological improvement at one year of follow-up. Key words: Infundibulo neurohypophysitis- gougerot sjogren’s syndrome – postpartum period - mycophenolate mofetil.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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