ECE2022 Eposter Presentations Late Breaking (59 abstracts)
Post-thyroidectomy hypocalcemia: a single-center retrospective study
Paloma Iglesias 1 , Ana Laura Salguero 1 , Jose Antonio Rosado 1 , Maria Merino 2 , Guadalupe Guijarro 1 , Cristina Navea 1 & Isabel Pavon 1
1Hospital Universitario de Getafe, Endocrinology, Madrid, Spain; 2Hospital Universitario de Getafe, Endocrinology, Spain
Background: Post surgery hypocalcemia is the most common sequel of thyroidectomy. An accurate prediction of hypocalcemia in the immediate postoperative period would enable the selection of patients for appropriate treatment and facilitate early discharge.
Objective: This study aims to investigate the prevalence of hypocalcemia after thyroidectomy and to identify potential risk factors.
Methods: This is a retrospective cohort study of 91 patients who underwent total thyroidectomy in a tertiary center between 2017 and 2019. Data were extracted from patient medical records. Hypocalcemia was evaluated in relation to risk factors (age, sex, body mass index and type of thyroid disease). Serum parathyroid hormone (iPTH) was measured 24 h (h) after surgery. Serum ionized calcium (Ca2+) was analyzed 8h, 24h and 48h post-surgery.
Results: Hypocalcemia was noted in 28 (30%) of 91 patients who underwent thyroidectomy. There was no significant relationship between the occurrence of hypocalcemia and age, sex, body mass index and type of thyroid disease. The best cut-off values of serum iPTH to predict hypocalcemia was found to be 19 pg/ml at 24h post total thyroidectomy with a sensitivity and specificity of 92.45% and 100%, respectively.
Conclusion: Clinical factors are not reliable predictive markers of immediate post-thyroidectomy hypocalcemia. Prediction of hypocalcemia using serum iPTH seems to be a promising approach. In our cohort, a cut-off value of 19 pg/ml at 24h after surgery showed a good sensitivity and specificity. Serum vitamin D levels were not performed preoperatively. This can be considered a limitation of our study.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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