ECE2022 Eposter Presentations Endocrine-Related Cancer (61 abstracts)
Bilateral localization of Leydig tumor in the testicles: Case Report
Fatima Zahra Outtaleb 1 , Amin Alami 2 , Zineb Bouchbika 2 , Nadia Benchakroun 2 , Hassan Jouhadi 2 , Nezha Tawfiq 2 , Souha Sahraoui 2 , Abdellatif Benider 2 & Hind Dehbi 1,3
1Ibn Rochd University Hospital, Laboratory of Medical Genetics, Casablanca, Morocco; 2Ibn Rochd University Hospital, Mohamed VI Oncology Center, Casablanca, Morocco; 3Faculty of Medicine and Pharmacy, Hassan II University, Cellular and Molecular Pathology Laboratory, Casablanca, Morocco
Testicular cancer represents 1% of male tumors. The bilateral testicular tumors are very rare (1 to 2% of cases), with a histological predominance of 90–95% of germ cell tumors. The objectives of this case report are to describe the clinical, paraclinical and the management of a rare neoplasic disease of the testicle; the bilateral Leydig tumor of the testicles. It is a 57-year-old patient with a family history of different neoplasms, including ovarian and breast cancer in siblings, and followed since the age of 51 for a Leydig tumor of the testicle, reveled by an indolor testicular mass of the right testicle, without any clinical signs of endocrine disorders. Ultrasound scrotal found a 30 mm left testicular hypoechoic nodule, testis law without particularity, The tumor markers and hormonal explorations were normal. Extension report without anomaly. A right orchiectomy was performed. 3 years later, he presented a second localization of a Leydig tumor in the left testicle, also treated by orchidectomy. No adjuvant treatment (radio or chemotherapy) was indicated. A hormone replacement therapy was also established. Currently, the patient is followed in the oncogenetic consultation, for the identification a possible hereditary predisposition of neoplasms. The Leydig cell tumors of the testicles are typically characterized by the association of a tumor testicular and clinical and biological endocrine signs. The typical manifestations in adult include a secondary feminization. But in 10% of case, the clinical presentation is limited to the testicular mass and only the histology confirms the diagnostic. The diagnosis of the leydigioma is histological but there is no clear limit between tumor benign and malignant, therefore, orchiectomy is the standard treatment and it is only the absence of long-term metastases that will confirm the benignity, prolonged monitoring is essential.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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