ECE2022 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (318 abstracts)
Correlation between pulse wave velocity and nephropathy in type 2 diabetes
Chayma Besrour 1 , Rojbi Imen 1 , Ben Ahmed Habib 2 , Mekni Sabrine 1 , Mchirgui Nadia 1 , Ben Nacef Ibtissem 1 & Khiari Karima 1
1Hospital Charles Nicolle, Endocrinology, Tunis, Tunisia; 2Hospital Charles Nicolle, Cardiology, Tunis, Tunisia
Introduction: Nephropathy is a kidney complication that affects up to 50% of people with diabetes during their lifetime. Diabetes is the first cause of kidney failure. The aim of this study was to examine the relationship between diabetic nephropathy (DN) and arterial stiffness.
Methods: We conducted a prospective study including 249 diabetic patients without macroangipathic complications, between July 2020 and May 2021. Using a SphygmoCor®XCEL device, we measured arterial stiffness directly by the carotid to femoral pulse wave velocity (cfPWV).
Results: The mean age of the study population was 57.53 ± 9.34 years (139 women and 110 men). The mean duration of the disease was 10.2 years. Diabetic nephropathy (DN) was found in 34.5 % of the patients. The mean microalbuminuria was 48.58±86.67 mg/g of creatinuria. CfPWV > 10 m/s was found in 96.5 % of the patients with DN. And the mean microalbuminuria in patients with cfPWV > 10 m/s was 52.36±90.17 mg/g of creatinuria. In this group, cfPWV was at 14.38 ± 2.70 m/s VS 13.25 ± 2.81 m/s in patients without DN (P=0.002). We did not find a correlation between cfPWV and the stage of the nephropathy. Moreover, the presence of arterial stiffness multiples by 5 the risk of diabetic nephropathy (Odds Ratio =5).
Conclusion: This study shows that arterial stiffness is higher in type 2 diabetic patients with diabetic nephropathy than in those without diabetic nephropathy. Indeed, an elevated microalbuminuria is a marker of arterial stiffness in the general population and in the diabetic and hypertensive population. Several studies have investigated the relationship between arterial stiffness in type 2 diabetics, but there is little information regarding the relationship between cfPWV and microalbuminuria.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more