Endocrine Abstracts

This article discusses the assessment of quality of life, psychological state and anxiety-depressive disorders in patients with metabolic syndrome. It is known that the prevalence of metabolic syndrome in different countries is about 30% and varies from included criteria. The problem of the quality of life of obese and overweight patients is relevant and socially significant. Research Methods The authors present the results of a study of 70 patients with MS and 36 apparently healthy volunteers who do not have concomitant diseases and are not obese. The study was conducted on the basis of the clinic of the Federal Research Center. Patients were examined, anthropometric parameters were determined (waist circumference, body weight) with an assessment of the quality of life (SF-36 questionnaire). The level of anxiety and depression was determined by the hospital anxiety and depression scale HADS.

Results: Analysis of the results revealed that most of the quality of life indicators were statistically significantly different in patients with metabolic syndrome relative to the control group. Thus, the indicators of the level of QoL are significantly higher in healthy individuals than in patients with obesity. Differences in all groups are significant (P≤0.05). It was found that the average level of parameters “physical functioning” decreased by 19.2% (P < 0.05), “role functioning” by 34.2% (P < 0.05), “general health” by 14.7% (P < 0.05), "vitality" by 16% (P < 0.05), "emotional functioning" by 53.1% (P < 0.05). The assessment of the level of anxiety and depression in patients with MS corresponded to the subclinically expressed level, and the level of depression exceeded the control group by 19%. The level of QoL in patients with obesity is significantly lower than in healthy individuals.

Conclusion: Assessment of the quality of life of patients with obesity and overweight is one of the most important factors in the integrative assessment of the condition of such patients. I would like to note that the higher the patient’s body weight, the lower his physical condition and the more pronounced concomitant diseases. Patients with MS are characterized by a decrease in quality of life indicators, subclinically expressed anxiety-depression. Patients require correction of psychological disorders, which will reduce the level of anxiety and depressive disorders, which will further improve the quality of life.