Endocrine Abstracts

Introduction: Low high-density lipoprotein (HDL) is a frequent metabolic abnormality, associated with diabetes, may increase the cardiovascular risk of patients with type 2 diabetes. We aimed in this study, determine the prevelence of hypo HDL cholesterol and assess the associated cardiovascular risk.

Method: It is a retrospective study, including 184 type 2 diabetic patients, conducted in the department C of the National Institute of Nutrition of Tunis during the year 2021. HypoHDl cholesterol was considred if the patients had HDLc (<40mg/dl (men); < 50mg/dl (women)). ResultsThe study included 184 patients (118 women, and 66 men), with mean of age 61 +/- 10 years. The prevalence of low HDL cholesterol was 44.6%. Patients with low HDl cholesterol had a slight female predominance (52.5%). Hypertension was present in 70% of patients. Patients were obese and overweight in 56% and 31% of cases, respectively with an average body mass index of 30.63 +/- 5. In addition, they had hepatic steatosis in 28% of cases. the majority of patients had a Glycated hemoglobin out of target (92.5%), with an average HB1AC 10.5 +/- 2%. Moreover a hyper LDL cholesterolemia and hypertriglyceridemia were noted in 39 and 63.4% respectively. coronary artery disease was present in 32.9% of patients.

Conclusion: Low HDlc is a common situation in type 2 diabetes and increases the cardiovascular risk in these patients.