Endocrine Abstracts

Introduction: Pancreatic diabetes is a special category of diabetes due to diseases of the exocrine pancreas, characterized by both insulin and glucagon deficiency and clinically could be very challenging to control. We present a case of a woman with pancreatic diabetes treated with sensor augmented pump therapy after undergoing total pancreatectomy for a nonfunctional pancreatic neuroendocrine tumor (NET).

Presentation: A sixty-one years old woman underwent two years ago total pancreatectomy for a non-functioning neuroendocrine tumor. Consequently she developed pancreatic diabetes and was treated with a basal - bolus insulin regime. Her diabetes was poorly controlled despite all efforts due to severe, frequent and sudden hypoglycaemic attacks, affecting her quality of life. Her HbA1c was 8.5% and her Time in Range (TIR) was 28%, Time above range (TAR) 56%, Time below range (TBR) 16%, Glucose management Indicator (GMI) 8.5%, Glucose Variability (GV) 34.1% and Average Glucose (AG) 233 mg/dl. To achieve a better management of her diabetes, a sensor augmented pump (SAP) therapy was initiated and she was greatly improved (TIR 60%, TAR 40%, TBR 0%, GMI 7.5%, GV 30.6% and AG 173 mg/dl) and hypoglycemia was not a problem any more. Conclusion:Treating patients with pancreatic diabetes could be very challenging. Sensor augmented pump therapy can greatly improve their glycemic control, but most of all their quality of life.