Endocrine Abstracts

Background: Magnesium deficiency is a common clinical electrolyte abnormality in critically ill patients, related to the higher mortality risk, which is easily ignored. We aimed to investigate the association between magnesium levels and mortality and morbidity in patients admitted to the (ICU) based on COVID-19 infection classification.

Method: A total of 69 patients admitted to the ICU of Shahid Mohammadi Hospital were included in the study. The serum magnesium was measured in IUC patients. Data on score systems SOFA and APACHE, length of ICU stay, and duration of mechanical ventilation was determined. The mortality and morbidity were determined in patients. Also, the COVID-19 infection was detected by PCR test.

Results: The mean±SD age of patients (34.8% male) was 52.56±16.43 years. Out of 69 patients, 18 patients (26.1%) died during hospitalization, and 24 patients (34.8%) required mechanical ventilation. The prevalence of COVID-19 infection was 39.1%(27 patients). Our results showed that there is no difference in serum magnesium in patients based on mortality status. Also, no difference was found in magnesium levels in patients based on most of the morbidities status; however, the magnesium level of patients with kidney failure was significantly higher than patients without kidney failure (P < 0.05). Based on the COVID-19 infection classification, there was only a positive correlation between Hypomagnesemia and the length of ICU hospitalization in patients without COVID-19 (P < 0.05). ConclusionOur findings showed no difference in magnesium levels of patients based on mortality status. Based on morbidities status, patients with kidney failure had higher serum magnesium than those without kidney failure. Also, our results showed no difference in magnesium levels of critically ill patients based on COVID-19 infection status.