Endocrine Abstracts

Introduction: Diabetic nephropathy is a a dreadfull complication of diabetes and it is the leading cause of chronic kidney disease worldwide. Hypertension is a major cause of progression of this complication.

Objective: To determine the prevalence of diabetic nephropathy, to search a correlation between the presence and duration of arterial hypertension and the occurrence of diabetic nephropathy.

Patients and methods: This is a retrospective study carried out about 184 type 2 diabetic patients, followed at the department C of the National Institute of Nutrition in Tunis.

Results: The mean age was 61±10 years, with a sex ratio M/F of 0.56. The mean duration of diabetes was 14±8 years, the mean glycated hemoglobin (HbA1c) was 10.6%. Nephropathy was present in 37% of cases. In the subpopulation of patients with nephropathy, it was noted that 67% of patients were at the stage of micro albuminuria, 44.2% were in renal failure, mean clearance of creatinine was 57 ml/min and 79% were hypertensive. The presence of nephropathy was correlated with the duration of evolution of hypertension (74% had a duration of evolution of more than 05 years) and 62% of patients were in blood pressure imbalance.

Conclusion: Blood pressure control is crucial in diabetic patients, it allows nephroprotection and an improvement of the cardiovascular prognosis.