ECE2022 Eposter Presentations Calcium and Bone (114 abstracts)
Hypoparathyroidism: about 61 cases
Mnif Fatma , Asma Zargni , Kawthar El ARBI , Mouna Elleuch , Raida Trigui , Nadia Charfi , Mouna Mnif , Nabila Rekik Majdoub , Faten Haj Kacem Akid & Mohamed Abid
Hedi Chaker Hospital, Diabetology and Endocrinology Department, Sfax, Tunisia
Introduction: Hypoparathyroidism (HPT) is an often under-diagnosed condition. It is imperative to diagnose it at an early stage and to initiate prompt treatment given the evolving potential of the disease.The aim of our study is to describe the epidemiological, clinical and paraclinical features of HPT.
Patients and Methods: This is a retrospective study of 61 observations of HPT collected at the endocrinology department during a 12-year period.
Results: The mean age of our patients at the time of diagnosis was 41 years and 6 months (extremes ranging from 13 to 80 years). HPT was more frequent in the age group 21-30 years. A clear female predominance was observed with a sex ratio of 4.5. The circumstances of discovery were mainly paresthesias (65%) and muscle cramps (62%). The majority of our patients (90%) had hypocalcemia with an average blood calcium level of 1.65 mmol/l (normal range 2.2-2.6 mmol/l). Hypophosphatemia was found in 52% of cases, and hypocalciuria in 80%. Low PTH was found in 72% of cases with a mean level of 9.48 pg/ml. Cervical surgery was responsible for a postoperative HPT in 74% of cases. However, 16% of the cases were idiopathic PTH. Autoimmune origin was observed in 3 cases (5%).
Discussion-conclusion: HPT is a rare and often asymptomatic disease, hence the interest of the calcemia analysis in front of even minor clinical signs.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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