Endocrine Abstracts

Objective: Adrenal venous sampling (AVP) is a reliable procedure to differentiate if in patients with primary aldosteronism (PA) aldosterone production is unilateral or bilateral and guide the treatment of these patients. Our objective was to describe their characteristics and the outcomes of the AVPs.

Methods and patients: Observational longitudinal clinical study between July 2020 and September 2021 in patients who underwent AVP in our Hospital.

Results: 10 patients included. Mean age: 50.9±14.67 years. 60% women. IMC: 26.64±4.05 kg/m². 80% patients with an adenoma in the CT: 20% in the right gland, 50% in the left and 10% in both. 20% of patients without adenoma in CT. Reason of PA screening: 40% resistant high blood pressure (HBP), 20% HBP and adrenal adenoma and 40% HPA and hypokalemia. All patients received HBP treatment. 70% of patients took potassium supplementation. In 90% of patients catheterization of both adrenal glands was successful. 66.7% of them showed a left lateralization. 33.3% with no lateralization. Among the 5 patients with successful AVS and adenoma in CT, in 4 of them AVS lateralization matched the image. In 1 patient AVS lateralized to the opposite side. In 1 patient AVS showed left lateralization although no adenoma was seen in CT.All patients with successful catheterization underwent surgery according to the AVS result. 71.4% of them could stop HBP medication.

Conclusion: – In spite of the limited number of AVS performed in our center, AVS is successful in most of the patients (90%) in our series.

– In most patients (80%) AVS lateralization results matched the side of the adenoma in the CT image if it was present. In one patient there was lateralization although no image was seen in CT.

– After surgery most patients in our series can stop their HBP medication.