Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2021) 77 P155 | DOI: 10.1530/endoabs.77.P155

SFEBES2021 Poster Presentations Adrenal and Cardiovascular (45 abstracts)

Adrenal insufficiency secondary to primary adrenal lymphoma

San Pyae , Fathi Abourawi & Deepak Pai


Diana, the Princess of Wales hospital, NHS Trust, Grimsby, United Kingdom


Primary adrenal lymphoma is a rare cause of adrenal insufficiency, accounting for only approximately 1% of non-Hodgkin lymphoma cases. Most common subtype of PAL is diffuse large B cell lymphoma. A 71-year-old gentleman with the past history of hypertension, type 2 DM and the incidental finding of adrenal hyperplasia, presented with the general ill health with lethargy, weight loss and reduced appetite. He has the past history of hypertension, type 2 DM and the incidental finding of adrenal hyperplasia. Examinations were unremarkable apart from the signs of dehydration and postural hypotension. Initial investigations showed normocytic anaemia of Hb 70g/l, hyponatraemia with Na level of 128 mmol/l. A short synthacth test revealed adrenal insufficiency. CT scan showed bilateral adrenal haemorrhages on a background of pre-existing adrenal hyperplasia. Given the engulfing nature of the left-sided haematoma underlying lymphoma cannot be excluded. Treatment with glucocorticoid and mineralocorticoid hormone replacement therapy was started. A subsequent FDG/PET showed intensely hypermetabolic disease in both adrenal glands further soft tissue disease in the retroperitoneum and mesentery. Appearances are in keeping with an aggressive lymphoma for proliferative disorder. CT guided left adrenal mass biopsy was done which revealed high grade diffuse B-cell Non-Hodgkin lymphoma (DLBCL). R-CHOP chemotherapy was planned by consulting haematology.

Volume 77

Society for Endocrinology BES 2021

Edinburgh, United Kingdom
08 Nov 2021 - 10 Nov 2021

Society for Endocrinology 

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