ECE2021 Audio Eposter Presentations Late Breaking (114 abstracts)
A case of pituitary xanthogranuloma diagnosed with diabetes insipidus
Kubra Turan 1 , Unzile Arifoglu 2 , Narin Nasiroglu Imga 2 , Belma Tural Balsak 2 , Denizhan Divanlioglu 3 , Oya Topaloglu 1 , Reyhan Ersoy 1 & Bekir Cakir 1
1Yildirim Beyazit University Faculty of Medicine, Ankara City Hospital, Clinics of Endocrinology and Metabolism, Ankara, Turkey; 2Ankara City Hospital, Clinics of Endocrinology and Metabolism, Ankara, Turkey; 3Ankara City Hospital, Clinics of Neurosurgery, Ankara, Turkey
Background
Pituitary xanthogranulomas are extremely rare tumors of the sellar region. A cystic mass lesion was found in the pituitary MRI of our patient diagnosed with central diabetes insipidus (DI). We aimed to present a case who was operated for a pituitary mass and diagnosed with sellar xanthogranuloma.
Case presentation
37-year-old female patient was applied to our outpatient clinic with complaints of polydipsia, polyuria and headache for 8 months. The anterior pituitary hormone levels were in normal. Plasma osmolarity: 291 mOsm/kg, urine osmolarity: 130 mOsm/kg, urine density: 1006 and serum electrolytes were in normal range. Pituitary MRI revealed a cystic mass lesion with prominent hyperintense mucoid content in T1-weighted sequences with a diameter of approximately 10 × 11 mm and completely obliterating the neurohypophysis in the posterior of the adenohypophysis. Also the cystic mass lesion showed expansion towards the posterior suprasellar system. Her visual field examination was found normal. The patient was admitted to our clinic for the water deprivation test. Complete central DI was diagnosed. Desmopressin treatment was started on. The clinic and laboratory findings of DI were improved after desmopressin treatment. The patient was evaluated by neurosurgery department. Transsphenoidal surgery was performed for the mass lesion in the pituitary. The pathology result was reported as sellar xanthogranuloma. Desmopressin therapy was continued in the postoperative period. Clinical and laboratory findings were found normal under desmopressin treatment. Pituitary MRI performed 3 months after the operation, no finding of residual-recurrent adenoma was detected in the sellar region.
Conclusion
Sellar xanthogranulomas are very rare seen intracranial tumors. They have not any typical radiological feature. Patients can present with clinical signs such as headache, visual disturbance, vomiting, DI and hypopituitarism.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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