ECE2021 Audio Eposter Presentations Thyroid (157 abstracts)
1Complejo Hospitalario de Toledo, Endocrinology and Nutrition, Spain; 2Complejo Hospitalario de Toledo, Pathology, Spain
Introduction
The association of autoimmune, nodular or neoplastic thyroid disease and primary hyperparathyroidism (PHPT) has been reported in 17 to 84% of cases. In the surgical treatment of PHPT, simultaneous thyroidectomy may be necessary to optimize surgical access and / or when there is abnormal thyroid pathology. On the other hand, an incomplete diagnosis in the previous study of PHPT increases the risk of not removing clinically significant thyroid lesions.
Objective
To analyze the prevalence of thyroid disease (TD) associated with PHPT in patients undergoing parathyroidectomy, as well as the frequency with which simultaneous thyroidectomy had to be performed.
Methods
The medical records of 156 patients diagnosed with PHPT and operated on in our Hospital between 2005 and 2017 were retrospectively reviewed. The statistical analysis was performed with the SPSS V21 program.
Results
The mean age was 56.4 years (± 12.7), with 80.3% being women. The prevalence of TD was 52.6% (n = 82), being significantly more frequent in women (89% vs 11%; P <0.01). Thyroid nodular disease (TND) was diagnosed in 36.5% (n = 57) (34% multinodular goitre and 2.5% single nodule). Autoimmune thyroid disease (ATD) in 23.6% (n = 37) and papillary thyroid cancer (PTC) in 3.2% (n = 5). Fifty-two patients (33.3%) underwent simultaneous total or partial thyroidectomy, of which 75% (n = 39) had TND. PTC was incidentally diagnosed in one patient. TND was diagnosed preoperatively by radiological imaging techniques in 92.3% (35 by ultrasound and 1 by CT scan).
Conclusions
1. In our series of PHPT patients undergoing surgery, TD was associated in more than half of the cases. 2. Simultaneous thyroidectomy was required in 33.3% of all parathyroidectomies performed, with only 1 case of malignant lesion detected incidentally. 3. These findings highlight the need for a pre-surgical diagnosis of TD in patients with PHPT who are going to be operated on.