ECE2021 Audio Eposter Presentations Thyroid (157 abstracts)
The impact of treatment adherence on the control of the thyroid function in Hashimoto’s thyroiditis patients
Chayma Besrour , Meriem Yazidi , Ibtissem Oueslati , Nadia Khessairi , Wafa Grira , Fatma Chaker & Melika Chihaoui
University of Tunis el Manar, Faculty of Medecine of Tunis, La Rabta Hospital, Endocrinology, Tunis, Tunisia
Hashimoto’s thyroiditis (HT) is a chronic disease that needs a daily substitution by thyroid hormones. The purpose of this study was to assess the level of therapeutic adherence to the hormonal treatment in HT patients and its impact on the thyroid function control.
Methods
It is a cross sectional study including 43 patients treated for hypothyroid Hashimoto’s thyroiditis by levothyroxine (LT4). The patient adherence to treatment was evaluated by using the Girerd questionnaire in its Tunisian version. The level of adherence was considered good if the score was equal to 0, medium if it was equal to 1 or 2, and poor if it was equal to 3 or more.
Results
The mean age of the study population was 50.0 ± 12.9 years (41 women and two men). The mean duration of the disease was 7.9 ± 6.3 years. The TSH level was above the therapeutic target in 19% of the patients. The adherence was good in 9% of the patients, medium in 44% of the patients and poor in 47% of the patients. A TSH level higher than the therapeutic target was found in 0% of subjects with a good therapeutic adherence level, 21% of subjects with a medium therapeutic adherence level and 20% of subjects with a poor therapeutic adherence level (P = 0.6).
Conclusion
Poor adherence to hormonal treatment is frequent in HT patients. However, its impact on the control of the thyroid function is uncertain. This, may be explained by the extended half-life of the levothyroxine which is between 6 and 7 days, allowing occasional forgetfulness.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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