Endocrine Abstracts

Introduction

Idiopathic short stature is a condition in which the height of the individual is more than 2 standard deviation below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present. The aim of this study is to describe the vitamin D profile of patients followed up for idiopathic short stature in the endocrinology department of Mohamed VI University Hospital Center.

Materials and methods

We have collected 62 patients admitted in the Endocrinology Department of Mohammed VI University Hospital of Oujda, for the management of idiopathic short stature. The data were collected and processed using SPSS software V21.

Results

The average age of the patients was 11 ± 3 years, with a sex ratio M/F of 1.48. The mean height of our patients in admission was 128 ± 20 cm and the average weight was 26 ± 8 kg. The average standard deviation score was 2.7 ± 0.7 for height and 2.3 ± 0.9 for weight. The median difference in bone age from chronological age was 45 months (from 9 months to 144 months). The insulin growth factor 1 (IGF1) was low relative to pubertal stage in 12.9% of patients. Bone X-rays were performed in all patients and did not reveal any abnormalities. A propranolol-glucagon test was performed in 78.8% of patients and an insulin hypoglycemia test was performed in 16.1% of patients. No growth hormone deficiency was detected. The mean vitamin D value was 20 ± 8 ng/ml, in 62.9% of patients the vitamin D value was in the range 10–30 ng/ml, in 1.6% of patients it was less than 10 ng/ml, and in 9.7% it was greater than 30 ng/ml. The reminder of the phosphocalcic lobaratory test was normal in all patients.

Conclusion

The results of our study highlighted the value of vitamin D dosing in the context of idiopathic short stature, in order to detect any deficiency which may affect our children’s growth.